Exercise-induced energy expenditure (ExEE) is commonly adopted as a mean to volitional body mass loss. ExEE can also modulate physical activity energy expenditure (PAEE) and potentially limit the rate of body mass loss. The detrimental effect of ExEE on PAEE may be more prevalent in women than in men. This study was to investigate the sex differences in regulation of PAEE and body mass change following an acute exercise-induced perturbation in energy balance.  In this 3-week study, 4 men and 6 women with body mass index (BMI) of 28.8 ± 2.3 kg/m² were required to exercise on a leg ergometer, expending 15% of their total daily energy expenditure (TDEE) in each exercise session of week two (Exercise week). Participants had to complete three exercise sessions within the same week and on non-consecutive days. PAEE was assessed via wrist-worn accelerometers over the entire study period. Resting metabolic rate (RMR) and body composition were measured at the beginning of the study. Men had significantly greater stature (p=0.021), body mass (p=0.035) and resting metabolic rate (RMR) (p=0.01) than women. Whereas women body fat % was significantly greater than men (p=0.004). At the end of the study, there was no significant difference body mass % change (p=0.409) and ExEE (p=0.91) between men and women. There was no significant main effect of time for PAEE (p=0.613), or between sex (p=0.470). Three bouts of ExEE performed within the same week did not alter PAEE in men and women with overweight and obesity.

The development and advancement of sports training over time have been accompanied by continuous innovations, which significantly contribute to improving athletic performance. In this process, research has played a crucial role in understanding the effectiveness of various training methods, including blood flow restriction (BFR) exercise, which is increasingly gaining attention due to its potential to enhance athletic performance. BFR training can be implemented in both: resistance exercise and endurance exercise. The studies discussed indicate a growing interest in the application of BFR through endurance type of exercise to enhance aerobic capacity.
This narrative review examined the role of BFR training in enhancing endurance performance by reviewing relevant literature. We performed a comprehensive search on PubMed and Google Scholar using keywords such as “Blood Flow Restriction”, “endurance exercise”, “aerobic capacity”, and “athletes”. The focus was on peer-reviewed articles published in the last decade that investigated the effects of BFR training on endurance and aerobic capacity, specifically within athletic populations. Studies included in this review were selected based on their relevance to BFR training and its impact on endurance performance, while those not directly related to BFR or involving non-athlete populations were excluded. Key findings concerning BFR training protocols and their impact on endurance metrics were summarized. This review aims to provide an overview of the current evidence regarding the effectiveness of BFR training in endurance exercise and its potential implications for optimizing athletic performance.
These investigations adopting BFR training show promising results, with several studies reporting significant improvements in key physiological parameters such as maximal oxygen consumption (VO₂ max) and muscular endurance.
Overall evidence suggests that integrating BFR training into endurance exercise training regimens holds potential for optimizing aerobic capacity in athletes.

Female reproductive hormones such as progesterone and estrogen play an important role in the body as they orchestrate functions of numerous cells including skeletal muscle cells. Onset of menses marks the beginning of reproductive life, whereas menopause marks its cessation. We distinguish three phases of the 28-day menstrual cycle namely follicular, ovulatory and luteal phases. The follicular phase is characterised by marked increases in estrogen, which triggers ovulation. During this phase, estrogen peaks, whereas progesterone levels are low. Following ovulation, the luteal phase commences marked by high progesterone levels and reduced estrogen. Indeed, these periodic fluctuations in reproductive hormones may affect rates of muscle protein synthesis and hence hinder sought adaptations such as skeletal muscle hypertrophy in female athletes. With the introduction of hormonal contraceptives, female athletes were able to have ameliorate the negative effects of the menstrual cycle by reducing menstrual cramping and bleeding. Hormonal contraceptives are constituted of a single or multiple synthetic hormones namely estrogen and progestin. Nevertheless, the impact of hormonal contraceptives on skeletal muscle hypertrophy remains elusive. In this review, we aim to present the potential implications of hormonal contraceptives on skeletal muscle hypertrophy.