Women generally live longer than men because of both biological and behavioural advantages; still womenís longer lives are not necessarily healthy lives. Considering that women from rural areas are often recognized as particularly vulnerable social groups concerning quality of life and physical activity, the study was conducted aiming to determine physical functioning and general health of women from urban and rural areas, as well as to examine differences between them in these health domains. Sample comprises of females aged 30 to 60 yrs, totally 146 participants (73 from urban areas, 73 from rural areas). For the purposes of this study two scales, Physical functioning and General health perceptions, from the SF-36 Health Survey. The results obtained show that significant differences between two groups of participant exist in both domains, with more positive self-perceptions of physical functioning in urban females and more positive global health perceptions in rural females. These results confirm that personal satisfaction and perception of oneís global health are affected not merely by the physical functioning, but by other health components as well.