Lipid profile alterations following aerobic and resistance training programmes among HIV- seropositive female patients

Elvis I. Agbonlahor • Oluwaseun Susan Kubeyinje

DOI: 10.31382/eqol.200602


This study was designed to assess the changes in lipid profile of HIV-seropositive patients following 6-week aerobic and resistance exercise training.

The pretest-posttest control-group design (experimental and control groups) was adopted. Sixty female HIV-seropositive patients in stage 1 and 2 of the disease registered in University of Benin Teaching Hospital participated in the study. They were randomly assigned into control and experimental groups. The experimental group exercised for One hour, three times a week for six weeks while the control group continued with their daily routine. The baseline intensity of the exercise was 60% of maximum Heart Rate (HRmax) and 60% 1RM and it was progressed by 10% every 3 weeks. Lipid profile were recorded at baseline and on completion of 6 weeks for both groups. The hypotheses were tested with inferential statistics of Analysis of variance.

The findings of this study revealed that short duration exercise training improved some of the components of the lipid profile (high density lipoprotein and triglycerides).

It was therefore concluded based on the findings of this study that health professionals should recommend exercise for female HIV-infected individuals due to the health benefits. Also, human kinetics specialists should design exercise programmes suitable for this special population.

Keywords: HIV- seropositive • lipid profile • aerobic and resistance Training


Bhattacherjee, A. (2012). Social science research: Principles, methods and practices (2ndEdition). Textbooks Collection. Book Error! Hyperlink reference not valid.. Accessed on 23rd March, 2019.

Bopp, C.M., Phillips, K.D., Fulk, L.J. & Hand, G.A. (2003). Clinical implications of  therapeutic exercise in HIV/AIDS. Journal of Association of Nurses AIDS Care, 14(1),73-8.

Ciccolo, J.T., Jowers, E.M. & Bartholomew, J.B. (2004). The Benefits of Exercise Training for Quality of Life in HIV/AIDS in the Post-HAART Era. Sports Medicine, 34(8), 487-499.

Denue, B.A., Alkali, M.B., Abjah, A.U., Kida, I.M., Ajayi, B. & Fate, B.Z. (2013). Changes in lipid profile and other biochemical parameters in HIV-1 infected patients newly commenced on HAART regimen. Infectious Diseases: Research and Treatment, 6, 7-14

Garcia, A., Fraga, G.A., Vieira, R.C., Silva, C.M.S., Trombeta. J.C., Navalta, J.W., Prestes, J. & Voltarelli, F.A. (2014). Effect of combined exercise training on immunological, physical and biochemical parameters in individuals with HIV/AIDS. Journal of Sports Sciences, 32(8), 785-792.

Hand, G.A., Lyerly, G.W. & Jaggers, J.R. (2009). Impact of aerobic and resistance exercise on the health of HIV infected persons. American Journal of Lifestyle Medicine. 3, 489-499.

Maduagwu, S.M., Kaidal, A., Gashau, W., Balami, A., Ojiakor, A.C., Denue, B.A. & Kida, I. (2015). Effect of Aerobic Exercise on CD4 Cell Count and Lipid Profile of HIV Infected Persons in North Eastern Nigeria. Journal of AIDS Clinical Research. 6,508.

Sellmeyer, D.E. & Grunfeld, C. (1996). Endocrine and metabolic disturbances in human immunodeficiency virus infection and the acquired immune deficiency syndrome. Endocrine Review, 17(5), 518–32.

Terry, L., Sprinz, E., Stein, R., Medeiros, N.B., Oliveira, J. &Ribeiro, J.P. (2006). Exercise training in HIV-1-infected individuals with dyslipidemia and lipodystrophy. Medical Science of Sports and Exercise. 38, 411-417.

Tiozzo, E., Jayaweera, D., Rodriguez, A., Konefal, J., Melillo, A.B., Dawn, S. et al. (2013). Short-term combined exercise   training improves the health of HIV-infected       patients. Journal of AIDS and HIV Research, 5(3), 80-89.