Bakhtyar Tartibian, Asghar Abbasi, and Hirash Nouri, Department of Physical Education and sport science., Urmia University, Urmia., Iran, Institute of Clinical and Experimental Transfusion Medicine (IKET), University of Tuebingen,
Otfried-Mueller Tuebingen, Germany
The influence of intensive Judo training on serum immunoglobulins IgG, IgM, and IgA was studied in 24
Judo fighters. Subjects were assigned to an exercise training group (EXE; n=12) and non-exercise control
group (Con; n=12). Subjects in EXE group participated in exercise sessions 4 days a week for 8 wk.
Serum samples were collected before, immediately and 1wk after study period. The IgG levels were
significantly increased immediately after exercise training (p=0.001) in EXE compared to Con. However,
IgM and IgA concentrations showed significant decrease immediately after exercise in EXE (p=0.001).
The concentrations of all immunoglobulins had returned to baseline by 1wk of recovery. In conclusion
the increased IgG levels are possibly due to isotype switching or a secondary antibody responses that
could be considered as enhancement in immune system function. However, chronic suppression of
immuniglobulins IgM and IgA may be mediated by hormonal changes associated with exhausting
Keywords: Exercise immunity; Judo Fighters; Serum Immunoglobulins
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